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MEfRVO is a serious eye condition that can quickly get worse or lead to a complete loss of vision.1,2 The good news is that treatment options are available, and you've taken steps to help manage your MEfRVO.3-6

What is MEfRVO?

MEfRVO occurs when a blood vessel in the retina becomes blocked by a blood clot (also called a retinal vein occlusion) and leaks fluid into the macula.7,8 Vision loss or blurring happens as the macula swells with the fluid.1,2 There are 2 types of MEfRVO: MEfBRVO and MEfCRVO.

What is Macular Edema following Central Retinal Vein Occlusion (MEfCRVO)?

MEfCRVO occurs when the central retinal vein becomes blocked by a blood clot.7 MEfCRVO occurs less often than Macular Edema following BRVO (MEfBRVO), making up 2 out of every 10 diagnosed cases of MEfRVO.9

What is Macular Edema following Branch Retinal Vein Occlusion (MEfBRVO)?

MEfBRVO occurs when one or more veins branching out from the central retinal vein become blocked by a blood clot.8 Most diagnoses (8 out of 10 cases) of MEfRVO are MEfBRVO.9

What can put you at risk for MEfRVO?5,6,10

Trust your eye care team

Your eye care team is there to help you

MEfRVO may lead to vision loss.1,2 But you can take important steps to help your vision.3-6

Living with MEfRVO

Your eye care team can help you manage your eye health and treat your eye condition. Your loved ones are there to support you, too. Talk with them so they know how to best help you manage living with MEfRVO.


What you may be seeing

Having MEfRVO may change the way you see the world

MEfRVO can cause vision problems and even a complete loss of vision. Symptoms may affect your ability to read, write, drive, and recognize faces.

See the world with symptoms of MEfRVO through virtual reality

Macular Edema following Retinal Vein Occlusion (MEfRVO) virtual reality app

Learn more about the common symptoms of MEfRVO by seeing life through In My Eyes. MEfRVO is a disease that can get worse, so taking action can make a difference. Share the app with your loved ones to help them better understand what you may be experiencing.


Monitoring your vision is important

Tests your doctor may use

Your doctor may use the following tests to diagnose and monitor your condition and check your treatment progress:

Visual acuity test

Visual
acuity test
11,12

Measures how well you see the letters on an eye chart from a distance.

Dilated eye exam

Dilated
eye exam
11,12

Your doctor puts drops into your eye to dilate (widen) the pupil. He or she can then see the back of the eye, including the retina, for signs of problems or changes.

Fundus photography

Fundus
photography
11,12

A special camera takes photos showing the inside of the back of the eye.

Fluorescein angiography

Fluorescein
angiography
11,12

Dye is used to show the blood vessels in the back of the eye.

Optical coherence tomography

Optical coherence
tomography
13

An imaging test that shows the layers and thickness of the retina.


Take action with the Amsler Grid

Because MEfRVO can get worse, it is important that you check your vision in between eye appointments.14 The Amsler Grid is a simple eye test you can do on your own at home every day.14

Follow the directions below to download your Amsler Grid. If you see any problem areas while you're giving yourself the test, mark them with a pencil on the Amsler Grid. If your vision is getting worse, contact your eye care team right away!

How to use your Amsler Grid

You or your loved ones can use the slider below get an idea of what MEfRVO can do to your vision.

Normal Vision

Impaired Vision

It's important to see your eye doctor regularly

With MEfRVO, it's vital to keep your appointments and stay on course with your doctor's recommended treatment plan.3,4


Tips to help with vision

Just a few changes may make a big difference in your daily routine

Control light, contrast, and glare15,16
Low vision lighting tip
  • Keep rooms evenly lit, use adjustable lamps for direct light, and use nightlights
  • Use contrasting colors around the house—for example, paint doorframes and railings a different color from walls
Take charge of your kitchen15,16
Low vision kitchen tip
  • Organize items on shelves in cabinets and in the refrigerator
  • Mark appliance dials with brightly colored stickers
Manage your medicines15,16
Low vision medication tip
  • Mark pill bottles with differently colored rubber bands or Velcro to tell them apart
  • Use large-print pill boxes
Improve your view15-19
Improving your vision tip
  • Read with a magnifying glass
  • Read large-print materials
  • Enlarge the type size on your computer, and maximize contrast settings
Stay organized15,16
Low vision organization tip
  • Keep commonly used items in the same easy-to-reach places
  • Remove clutter, cords, and throw rugs
When you are out and about15,20
Living with low eye sight tip
  • Carry a magnifying device and a penlight or small flashlight
  • Wear sunglasses to reduce glare
  • Talk to your retina specialist about driving, and avoid driving at night

Sign up for more information

Get the latest materials and communications about EYLEA – and a complimentary pocket magnifier, too.

Important Safety Information
  • EYLEA® (aflibercept) Injection is a prescription medication administered by injection into the eye. You should not use EYLEA if you have an infection in or around the eye, eye pain or redness, or known allergies to any of the ingredients in EYLEA, including aflibercept.
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Important Safety Information
  • EYLEA® (aflibercept) Injection is a prescription medication administered by injection into the eye. You should not use EYLEA if you have an infection in or around the eye, eye pain or redness, or known allergies to any of the ingredients in EYLEA, including aflibercept.
  • Injection into the eye with EYLEA can result in an infection in the eye and retinal detachment (separation of retina from back of the eye). Inflammation in the eye has been reported with the use of EYLEA.
  • In some patients, injections with EYLEA may cause a temporary increase in eye pressure within 1 hour of the injection. Sustained increases in eye pressure have been reported with repeated injections, and your doctor may monitor this after each injection.
  • There is a potential risk of serious and sometimes fatal side effects related to blood clots, leading to heart attack or stroke in patients receiving EYLEA.
  • Serious side effects related to the injection procedure with EYLEA are rare but can occur including infection inside the eye and retinal detachment.
  • The most common side effects reported in patients receiving EYLEA are increased redness in the eye, eye pain, cataract, moving spots in the field of vision, increased pressure in the eye, and vitreous (gel-like substance) detachment.
  • It is important that you contact your doctor right away if you think you might be experiencing any side effects, including eye pain or redness, light sensitivity, or blurring of vision, after an injection.
  • EYLEA is for prescription use only. For additional safety information, please talk to your doctor and see the full Prescribing Information for EYLEA.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Indications

EYLEA® (aflibercept) Injection is a prescription medicine approved for the treatment of patients with:

  • Wet Age-related Macular Degeneration (AMD): The recommended dose for EYLEA is 2 mg administered by injection in the eye every 2 months (8 weeks) following 3 initial monthly (every 4 weeks) injections. EYLEA may be dosed once per month, but in most patients, additional benefit was not seen with this dosing plan. Some patients may need monthly (every 4 weeks) dosing after the first 3 months (12 weeks).
  • Macular Edema following Retinal Vein Occlusion (RVO): The recommended dose for EYLEA is 2 mg administered by injection in the eye monthly (every 4 weeks).
  • Diabetic Macular Edema (DME) and Diabetic Retinopathy (DR) in patients with DME: The recommended dose for EYLEA is 2 mg administered by injection in the eye every 2 months (8 weeks) following 5 initial monthly (every 4 weeks) injections. EYLEA may be dosed once per month, but in most patients, additional benefit was not seen with this dosing plan. Some patients may need monthly (every 4 weeks) dosing after the first 5 months (20 weeks).
Please see the full Prescribing Information for EYLEA.

The information contained herein is provided for general educational purposes. If you have any questions, talk to your doctor.

References:
  1. Central retinal vein occlusion (CRVO) symptoms. American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/central-retinal-vein-occlusion-symptoms. Accessed October 5, 2016.
  2. Branch retinal vein occlusion (BRVO) symptoms. American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/branch-retinal-vein-occlusion-symptoms. Accessed October 5, 2016.
  3. Central retinal vein occlusion (CRVO) treatment. American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/central-retinal-vein-occlusion-treatment. Accessed October 5, 2016.
  4. Branch retinal vein occlusion (BRVO) treatment. American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/branch-retinal-vein-occlusion-treatment. Accessed October 5, 2016.
  5. Who is at risk for central retinal vein occlusion (CRVO)? American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/central-retinal-vein-occlusion-risk. Accessed October 5, 2016.
  6. Who is at risk for branch retinal vein occlusion (BRVO)? American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/branch-retinal-vein-occlusion-risk. Accessed October 5, 2016.
  7. What is central retinal vein occlusion (CRVO)? American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/what-is-central-retinal-vein-occlusion. Accessed October 5, 2016.
  8. What is branch retinal vein occlusion (BRVO)? American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/what-is-branch-retinal-vein-occlusion. Accessed October 5, 2016.
  9. Sophie R, Campochiaro PA. Treatment of macular edema following branch retinal vein occlusion. US Ophthalmic Review. 2013;6(2):148-153.
  10. Central retinal vein occlusion. Prevent Blindness Web site. http://www.preventblindness.org/central-retinal-vein-occlusion. Accessed October 5, 2016.
  11. Central retinal vein occlusion (CRVO) diagnosis. American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/central-retinal-vein-occlusion-diagnosis. Accessed October 5, 2016.
  12. Branch retinal vein occlusion (BRVO) diagnosis. American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/branch-retinal-vein-occlusion-diagnosis. Accessed October 5, 2016.
  13. What is optical coherence tomography? American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/treatments/what-is-optical-coherence-tomography. Accessed October 5, 2016.
  14. Facts about macular edema. National Institutes of Health, National Eye Institute Web site. https://nei.nih.gov/health/macular-edema/fact_sheet. Accessed October 5, 2016.
  15. Low vision aids and low vision rehabilitation. American Academy of Ophthalmology (AAO EyeSmart) Web site. http://www.aao.org/eye-health/diseases/low-vision-aids-rehabilitation. Accessed October 5, 2016.
  16. Tips for living life to its fullest: tips for low vision. American Occupational Therapy Association (AOTA) Web site. https://www.aota.org/~/media/Corporate/Files/AboutOT/consumers/Adults/LowVision/Low%20Vision%20Tip%20Sheet.ashx. Accessed October 5, 2016.
  17. Options for reading on the Internet with a computer. American Foundation for the Blind, VisionAware Web site. http://www.visionaware.org/info/everyday-living/helpful-products/using-a-computer/options-for-reading-on-the-internet/1245. Accessed October 5, 2016.
  18. Windows accessibility options for people who are blind or have low vision. American Foundation for the Blind, VisionAware Web site. http://www.afb.org/info/living-with-vision-loss/using-technology/using-a-computer/part-ii-for-the-experienced-computer-user-with-a-new-visual-impairment/windows-accessibility-options/12345. Accessed October 5, 2016.
  19. Apple OS X accessibility options for people who are blind or have low vision. American Foundation for the Blind, VisionAware Web site. http://www.afb.org/info/living-with-vision-loss/using-technology/using-a-computer/part-ii-for-the-experienced-computer-user-with-a-new-visual-impairment/apple-os-x-accessibility-options/12345. Accessed October 5, 2016.
  20. Wolfe PR. Macular Disease: Practical Strategies for Living With Vision Loss. 2nd ed. New Richmond, WI: Park Publishing, Inc.; 2011.